Application of biomarkers for improving risk assessments of chemicals under the Water Framework Directive: a case study.

作者: Josephine A. Hagger , Malcolm B. Jones , David Lowe , D.R. Paul Leonard , Richard Owen

DOI: 10.1016/J.MARPOLBUL.2008.03.040

关键词:

摘要: To answer the requirement of European Commission's Water Framework Directive (WFD) for biological-effects endpoints to classify ecological health aquatic ecosystems, we propose biomarker response index (BRI). The BRI, based on a suite biomarkers at different levels biological individual level, provides an integrated relative measure general status coastal invertebrates. Using mussels (Mytilus edulis) from 10 estuaries classified by Environment Agency England and Wales under WFD was compared. Eight sites were healthier than predicted two showed similar that point-source pollution risk classification. Results indicate BRI offers potential organism can be used in monitoring as additional aid reduce uncertainty defining classification provide better evidence existing impact.

参考文章(52)
K. Broeg, H.v. Westernhagen, S. Zander, W. Körting, A. Koehler, The “bioeffect assessment index” (BAI): A concept for the quantification of effects of marine pollution by an integrated biomarker approach Marine Pollution Bulletin. ,vol. 50, pp. 495- 503 ,(2005) , 10.1016/J.MARPOLBUL.2005.02.042
Josephine A. Hagger, Michael H. Depledge, Tamara S. Galloway, Toxicity of tributyltin in the marine mollusc Mytilus edulis. Marine Pollution Bulletin. ,vol. 51, pp. 811- 816 ,(2005) , 10.1016/J.MARPOLBUL.2005.06.044
Paul I. Countryman, John A. Heddle, The production of micronuclei from chromosome aberrations in irradiated cultures of human lymphocytes. Mutation Research. ,vol. 41, pp. 321- 331 ,(1976) , 10.1016/0027-5107(76)90105-6
Stefano Bonacci, Mark A Browne, Awantha Dissanayake, Josephine A Hagger, Ilaria Corsi, Silvano Focardi, Tamara S Galloway, None, Esterase activities in the bivalve mollusc Adamussium colbecki as a biomarker for pollution monitoring in the Antarctic marine environment. Marine Pollution Bulletin. ,vol. 49, pp. 445- 455 ,(2004) , 10.1016/J.MARPOLBUL.2004.02.033
George L. Ellman, K.Diane Courtney, Valentino Andres, Robert M. Featherstone, A new and rapid colorimetric determination of acetylcholinesterase activity Biochemical Pharmacology. ,vol. 7, pp. 88- 95 ,(1961) , 10.1016/0006-2952(61)90145-9
Jon Grant, The relationship of bioenergetics and the environment to the field growth of cultured bivalves Journal of Experimental Marine Biology and Ecology. ,vol. 200, pp. 239- 256 ,(1996) , 10.1016/S0022-0981(96)02660-3
Tamara S Galloway, Rebecca J Brown, Mark A Browne, Awantha Dissanayake, David Lowe, Michael H Depledge, Malcolm B Jones, None, The ECOMAN project: A novel approach to defining sustainable ecosystem function. Marine Pollution Bulletin. ,vol. 53, pp. 186- 194 ,(2006) , 10.1016/J.MARPOLBUL.2005.09.036