IFN-γ-Dependent Inhibition of Tumor Angiogenesis by Tumor-Infiltrating CD4+ T Cells Requires Tumor Responsiveness to IFN-γ
作者： Gregory L. Beatty , Yvonne Paterson
DOI: 10.4049/JIMMUNOL.166.4.2276
关键词:
摘要: … This observation implies that host cells are the targets of IFN-γ rather than tumor cells, which … outgrowth by inhibiting angiogenesis while specifically targeting the killing of tumor cells will …
aai.org
jimmunol.org 参考文章(63)
K Strommer, C Siepl, I Heid, A Fontana, S Bodmer, N de Tribolet, K Frei, Immunosuppression and transforming growth factor-beta in glioblastoma. Preferential production of transforming growth factor-beta 2. Journal of Immunology. ,vol. 143, pp. 3222- 3229 ,(1989)
E. J. Manseau, K. P. Claffey, K. Tognazzi, Kiang-Teck Yeo, L. F. Brown, H. F. Dvorak, L. F. Del Aguila, Expression of vascular permeability factor/vascular endothelial growth factor by melanoma cells increases tumor growth, angiogenesis, and experimental metastasis. Cancer Research. ,vol. 56, pp. 172- 181 ,(1996)
M A Cheever, P D Greenberg, Treatment of disseminated leukemia with cyclophosphamide and immune cells: tumor immunity reflects long-term persistence of tumor-specific donor T cells. Journal of Immunology. ,vol. 133, pp. 3401- 3407 ,(1984)
Günter J. Hämmerling, Klas Kärre, Knut Sturmhöfel, Hans Gustaf Ljunggren, Elisabeth Wolpert, Transfection of β2-microglobulin restores IFN-mediated protection from natural killer cell lysis in YAC-1 lymphoma variants Journal of Immunology. ,vol. 145, pp. 380- 386 ,(1990)
H Tahara, H D Edington, M J Brunda, S F Wolf, R D Schreiber, W J Storkus, M K Gately, M A Nalesnik, T G McKinney, C L Nastala, Recombinant IL-12 administration induces tumor regression in association with IFN-gamma production. Journal of Immunology. ,vol. 153, pp. 1697- 1706 ,(1994)
A Will, M Röllinghoff, F Horn, U Hemmann, A Gessner, Intracellular murine IFN-gamma mediates virus resistance, expression of oligoadenylate synthetase, and activation of STAT transcription factors. Journal of Immunology. ,vol. 157, pp. 4576- 4583 ,(1996)
John Paul Ridge, Francesca Di Rosa, Polly Matzinger, A conditioned dendritic cell can be a temporal bridge between a CD4 + T-helper and a T-killer cell Nature. ,vol. 393, pp. 474- 478 ,(1998) , 10.1038/30989
Stephen P. Schoenberger, Rene E. M. Toes, Ellen I. H. van der Voort, Rienk Offringa, Cornelis J. M. Melief, T-cell help for cytotoxic T lymphocytes is mediated by CD40–CD40L interactions Nature. ,vol. 393, pp. 480- 483 ,(1998) , 10.1038/31002
A Yoshimura, E Nakayama, H Shiku, Rejection of an IA+ variant line of FBL-3 leukemia by cytotoxic T lymphocytes with CD4+ and CD4-CD8- T cell receptor-alpha beta phenotypes generated in CD8-depleted C57BL/6 mice. Journal of Immunology. ,vol. 150, pp. 4900- 4910 ,(1993)
Steven A. Rosenberg, Jeffrey S. Weber, Modulation of Murine Tumor Major Histocompatibility Antigens by Cytokines in Vivo and in Vitro Cancer Research. ,vol. 48, pp. 5818- 5824 ,(1988)