Corticotrophins and corticosteroids

摘要: Publisher Summary This chapter discusses corticotrophins and corticosteroids. Corticosteroids are widely prescribed drugs. They exert multiple pharmacological effects their potency is considerable. alone could account for an array of adverse reactions, but the problem complicated by fact that corticosteroids often with expectations far greater than deserved. Dosages excessive, treatment periods unnecessarily extended, new therapeutic indications continuously being explored, sometimes without justification. The benefits derived from corticosteroid therapy beyond question, so many risks associated it, much more information will be needed before benefit-risk relationship can accurately assessed in various situations. Anaphylactic allergic reactions to intravenous continue reported. Aspirin sensitivity or atopy was a feature found all these patients, reports add little what known about predisposition aspirin-sensitive patients true nature this reaction. A review 30 who had generalized allergic-like systemic concludes seem qualify as serves reminder sodium succinate salts not only agents incriminated, severe also occur after oral doses sensitive patients. Central serous choroidopathy relatively rare disease unknown etiology steroid treatment. report Japan includes 5 cases which developed 1 month high-dose prednisolone