Amygdalar circuits required for either consolidation or extinction of taste aversion memory are not required for reconsolidation.

作者: Amir Bahar , Nimrod Dorfman , Yadin Dudai

DOI: 10.1111/J.0953-816X.2004.03215.X

关键词:

摘要: Recent reports have revitalized the debate on whether, for each item in memory, consolidation occurs just once, or upon their activation retrieval, items memory undergo reconsolidation. Further, it has been recently reported that following retrieval absence of reinforcer, activated can either reconsolidate extinguish, depending training history. This raises question whether consolidation, extinction and reconsolidation share neuronal mechanisms, moreover, recapitulates consolidation. In conditioned taste aversion (CTA), depends protein synthesis central nucleus amygdala, whereas basolateral nuclei amygdala. Here we show inhibition these no effect CTA under conditions initiate implies does not recapitulate are different processes.

参考文章(17)
Stephen M. Taubenfeld, Maria H. Milekic, Barbara Monti, Cristina M. Alberini, The consolidation of new but not reactivated memory requires hippocampal C/EBPβ Nature Neuroscience. ,vol. 4, pp. 813- 818 ,(2001) , 10.1038/90520
Karim Nader, Glenn E. Schafe, Joseph E. Le Doux, Fear memories require protein synthesis in the amygdala for reconsolidation after retrieval Nature. ,vol. 406, pp. 722- 726 ,(2000) , 10.1038/35021052
Raphael Lamprecht, Shoshi Hazvi, Yadin Dudai, cAMP Response Element-Binding Protein in the Amygdala Is Required for Long- but not Short-Term Conditioned Taste Aversion Memory The Journal of Neuroscience. ,vol. 17, pp. 8443- 8450 ,(1997) , 10.1523/JNEUROSCI.17-21-08443.1997
Mark Eisenberg, Tali Kobilo, Diego E Berman, Yadin Dudai, Stability of retrieved memory: inverse correlation with trace dominance. Science. ,vol. 301, pp. 1102- 1104 ,(2003) , 10.1126/SCIENCE.1086881
S. J. Sara, Retrieval and reconsolidation: toward a neurobiology of remembering. Learning & Memory. ,vol. 7, pp. 73- 84 ,(2000) , 10.1101/LM.7.2.73
Kerrie L. Thomas, Mercedes Arroyo, Barry J. Everitt, Induction of the learning and plasticity-associated gene Zif268 following exposure to a discrete cocaine-associated stimulus. European Journal of Neuroscience. ,vol. 17, pp. 1964- 1972 ,(2003) , 10.1046/J.1460-9568.2003.02617.X
Amir Bahar, Anat Samuel, Shoshi Hazvi, Yadin Dudai, The amygdalar circuit that acquires taste aversion memory differs from the circuit that extinguishes it. European Journal of Neuroscience. ,vol. 17, pp. 1527- 1530 ,(2003) , 10.1046/J.1460-9568.2003.02551.X
Martha L Escobar, Ileana Alcocer, Vincent Chao, None, The NMDA receptor antagonist CPP impairs conditioned taste aversion and insular cortex long-term potentiation in vivo. Brain Research. ,vol. 812, pp. 246- 251 ,(1998) , 10.1016/S0006-8993(98)00931-7