Imaging, spectroscopy, mechanical, alignment and biocompatibility studies of electrospun medical grade polyurethane (Carbothane™ 3575A) nanofibers and composite nanofibers containing multiwalled carbon nanotubes.
作者： Faheem A. Sheikh , Javier Macossay , Travis Cantu , Xujun Zhang , M. Shamshi Hassan
DOI: 10.1016/J.JMBBM.2014.10.012
关键词:
摘要: Abstract In the present study, we discuss electrospinning of medical grade polyurethane (Carbothane™ 3575A) nanofibers containing multi-walled-carbon-nanotubes (MWCNTs). A simple method that does not depend on additional foreign chemicals has been employed to disperse MWCNTs through high intensity sonication. Typically, a polymer solution consisting polymer/MWCNTs electrospun form nanofibers. Physiochemical aspects prepared were evaluated by SEM, TEM, FT-IR and Raman spectroscopy, confirming MWCNTs. The biocompatibility cell attachment produced nanofiber mats investigated while culturing them in presence NIH 3T3 fibroblasts. results from these tests indicated non-toxic behavior had significant cells towards incorporation into polymeric led an improvement tensile stress 11.40±0.9 51.25±5.5 MPa. Furthermore, complete alignment resulted enhancement 72.78±5.5 MPa. Displaying attributes mechanical properties nature are recommended for ideal candidate future tendon ligament grafts.
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sci-hub.se 参考文章(34)
Formhals Anton, Process and apparatus for preparing artificial threads ,(1930)
Formhals Anton, Artificial thread and method of producing same ,(1937)
Quynh P. Pham, Upma Sharma, Antonios G. Mikos, Electrospinning of polymeric nanofibers for tissue engineering applications: a review. Tissue Engineering. ,vol. 12, pp. 1197- 1211 ,(2006) , 10.1089/TEN.2006.12.1197
Mohammad Moniruzzaman, Jayanta Chattopadhyay, W. Edward Billups, Karen I. Winey, Tuning the Mechanical Properties of SWNT/Nylon 6,10 Composites with Flexible Spacers at the Interface Nano Letters. ,vol. 7, pp. 1178- 1185 ,(2007) , 10.1021/NL062868E
Chengwei Yang, Guoying Deng, Weiming Chen, Xiaojian Ye, Xiumei Mo, A novel electrospun-aligned nanoyarn-reinforced nanofibrous scaffold for tendon tissue engineering. Colloids and Surfaces B: Biointerfaces. ,vol. 122, pp. 270- 276 ,(2014) , 10.1016/J.COLSURFB.2014.06.061
Z.X. Meng, W. Zheng, L. Li, Y.F. Zheng, Fabrication and characterization of three-dimensional nanofiber membrance of PCL-MWCNTs by electrospinning Materials Science and Engineering: C. ,vol. 30, pp. 1014- 1021 ,(2010) , 10.1016/J.MSEC.2010.05.003
Aihua Liu, Itaru Honma, Masaki Ichihara, Haoshen Zhou, Poly(acrylic acid)-wrapped multi-walled carbon nanotubes composite solubilization in water : definitive spectroscopic properties Nanotechnology. ,vol. 17, pp. 2845- 2849 ,(2006) , 10.1088/0957-4484/17/12/003
Travis J. Sill, Horst A. von Recum, Electrospinning: Applications in drug delivery and tissue engineering Biomaterials. ,vol. 29, pp. 1989- 2006 ,(2008) , 10.1016/J.BIOMATERIALS.2008.01.011
Nasser AM Barakat, Muzafar A Kanjwal, Faheem A Sheikh, Hak Yong Kim, None, Spider-net within the N6, PVA and PU electrospun nanofiber mats using salt addition: Novel strategy in the electrospinning process Polymer. ,vol. 50, pp. 4389- 4396 ,(2009) , 10.1016/J.POLYMER.2009.07.005
Mingjing Yang, Ze Zhang, Charles Hahn, Gaétan Laroche, Martin W King, Robert Guidoin, None, Totally implantable artificial hearts and left ventricular assist devices: selecting impermeable polycarbonate urethane to manufacture ventricles. Journal of Biomedical Materials Research. ,vol. 48, pp. 13- 23 ,(1999) , 10.1002/(SICI)1097-4636(1999)48:1<13::AID-JBM4>3.0.CO;2-4