Identification of a novel HIP1-ALK fusion variant in Non-Small-Cell Lung Cancer (NSCLC) and discovery of ALK I1171 (I1171N/S) mutations in two ALK-rearranged NSCLC patients with resistance to Alectinib.

作者: Sai-Hong Ignatius Ou , Samuel J. Klempner , Joel R. Greenbowe , Michele Azada , Alexa B. Schrock

DOI: 10.1097/JTO.0000000000000368

关键词:

摘要: … kinase (ALK) in non–small-cell lung cancer (NSCLC). To date, two variants of HIP1-ALK (H21; … However, the response of patients with NSCLC harboring HIP1-ALK to ALK inhibitors and …

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