HIP1–ALK, A Novel ALK Fusion Variant that Responds to Crizotinib
作者： Douglas D. Fang , Bin Zhang , Qingyang Gu , Maruja Lira , Qiang Xu
DOI: 10.1097/JTO.0000000000000087
关键词: Pathology 、 Crizotinib 、 Reverse transcription polymerase chain reaction 、 ALK inhibitor 、 Biology 、 Lung cancer 、 Carcinogenesis 、 Anaplastic lymphoma kinase 、 Cancer research 、 Exon 、 Fusion gene
摘要: Introduction: The aim of this study was to identify anaplastic lymphoma kinase (ALK) rearrangements in lung cancer patient-derived xenograft (PDX) models and to explore their …
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Fujimoto J, Shiota M, Mori S, Yamamoto T, Satoh H, Semba T, Hyperphosphorylation of a Novel 80 kDa Protein-Tyrosine Kinase Similar to Ltk in a Human Ki-1 Lymphoma Cell Line, AMS3 Oncogene. ,vol. 9, pp. 1567- 1574 ,(1994)
Zhigui Ma, Jan Cools, Peter Marynen, Xiaoli Cui, Reiner Siebert, Stefan Gesk, Brigitte Schlegelberger, Benjamin Peeters, Christiane De Wolf-Peeters, Iwona Wlodarska, Stephan W. Morris, Inv(2)(p23q35) in anaplastic large-cell lymphoma induces constitutive anaplastic lymphoma kinase (ALK) tyrosine kinase activation by fusion to ATIC, an enzyme involved in purine nucleotide biosynthesis. Blood. ,vol. 95, pp. 2144- 2149 ,(2000) , 10.1182/BLOOD.V95.6.2144
Daisy Wing-Sze Wong, Elaine Lai-Han Leung, Sunny Kit-Man Wong, Vicky Pui-Chi Tin, Alan Dart-Loon Sihoe, Lik-Cheung Cheng, Joseph Siu-Kie Au, Lap-Ping Chung, Maria Pik Wong, A novel KIF5B-ALK variant in nonsmall cell lung cancer. Cancer. ,vol. 117, pp. 2709- 2718 ,(2011) , 10.1002/CNCR.25843
Luis Hernández, Magda Pinyol, Silvia Hernández, Silvia Beà, Karen Pulford, Andreas Rosenwald, Laurence Lamant, Brunangelo Falini, German Ott, David Y. Mason, Georges Delsol, Elias Campo, TRK-fused gene (TFG) is a new partner of ALK in anaplastic large cell lymphoma producing two structurally different TFG-ALK translocations. Blood. ,vol. 94, pp. 3265- 3268 ,(1999) , 10.1182/BLOOD.V94.9.3265
Theodora S. Ross, Olivier A. Bernard, Roland Berger, D. Gary Gilliland, Fusion of Huntingtin Interacting Protein 1 to Platelet-Derived Growth Factor β Receptor (PDGFβR) in Chronic Myelomonocytic Leukemia With t(5;7)(q33;q11.2) Blood. ,vol. 91, pp. 4419- 4426 ,(1998) , 10.1182/BLOOD.V91.12.4419.412K43_4419_4426
Christian Touriol, Catherine Greenland, Laurence Lamant, Karen Pulford, Frédéric Bernard, Thérèse Rousset, David Y. Mason, Georges Delsol, Further demonstration of the diversity of chromosomal changes involving 2p23 in ALK-positive lymphoma: 2 cases expressing ALK kinase fused to CLTCL (clathrin chain polypeptide-like). Blood. ,vol. 95, pp. 3204- 3207 ,(2000) , 10.1182/BLOOD.V95.10.3204
Theodora S. Ross, D. Gary Gilliland, Transforming properties of the huntingtin interacting protein 1/platelet-derived growth factor β receptor fusion protein Journal of Biological Chemistry. ,vol. 274, pp. 22328- 22336 ,(1999) , 10.1074/JBC.274.32.22328
Florence Armstrong, Laurence Lamant, Corinne Hieblot, Georges Delsol, Christian Touriol, TPM3-ALK expression induces changes in cytoskeleton organisation and confers higher metastatic capacities than other ALK fusion proteins European Journal of Cancer. ,vol. 43, pp. 640- 646 ,(2007) , 10.1016/J.EJCA.2006.12.005
Hiroyuki Mano, Non-solid oncogenes in solid tumors : EML4-ALK fusion genes in lung cancer Cancer Science. ,vol. 99, pp. 2349- 2355 ,(2008) , 10.1111/J.1349-7006.2008.00972.X
Frederic Tort, Elias Campo, Brad Pohlman, Eric Hsi, Heterogeneity of genomic breakpoints in MSN-ALK translocations in anaplastic large cell lymphoma Human Pathology. ,vol. 35, pp. 1038- 1041 ,(2004) , 10.1016/J.HUMPATH.2004.05.006