Non-solid oncogenes in solid tumors : EML4-ALK fusion genes in lung cancer

作者: Hiroyuki Mano

DOI: 10.1111/J.1349-7006.2008.00972.X

关键词:

摘要: … of EML4–ALK. Interestingly, the ALK part of our EML4–ALK cDNA starts from exon 20 of ALK, which is also the fusion point in the vast majority of the other ALK fusion cDNA molecules, …

参考文章(71)
Kimberley A. Cataldo, Syed M. Jalal, Mark E. Law, Stephen M. Ansell, David J. Inwards, Miriam Fine, Daniel A. Arber, Karen A. Pulford, John G. Strickler, Detection of t(2;5) in anaplastic large cell lymphoma: comparison of immunohistochemical studies, FISH, and RT-PCR in paraffin-embedded tissue. The American Journal of Surgical Pathology. ,vol. 23, pp. 1386- 1392 ,(1999) , 10.1097/00000478-199911000-00009
Shin-ichiro Fujiwara, Yoshihiro Yamashita, Young Lim Choi, Tomoaki Wada, Ruri Kaneda, Shuji Takada, Yukio Maruyama, Keiya Ozawa, Hiroyuki Mano, None, Transforming activity of the lymphotoxin-β receptor revealed by expression screening Biochemical and Biophysical Research Communications. ,vol. 338, pp. 1256- 1262 ,(2005) , 10.1016/J.BBRC.2005.10.080
Felix Mitelman, Recurrent chromosome aberrations in cancer. Mutation Research-reviews in Mutation Research. ,vol. 462, pp. 247- 253 ,(2000) , 10.1016/S1383-5742(00)00006-5
U. McDermott, S. V. Sharma, L. Dowell, P. Greninger, C. Montagut, J. Lamb, H. Archibald, R. Raudales, A. Tam, D. Lee, S. M. Rothenberg, J. G. Supko, R. Sordella, L. E. Ulkus, A. J. Iafrate, S. Maheswaran, C. N. Njauw, H. Tsao, L. Drew, J. H. Hanke, X.-J. Ma, M. G. Erlander, N. S. Gray, D. A. Haber, J. Settleman, Identification of genotype-correlated sensitivity to selective kinase inhibitors by using high-throughput tumor cell line profiling Proceedings of the National Academy of Sciences of the United States of America. ,vol. 104, pp. 19936- 19941 ,(2007) , 10.1073/PNAS.0707498104
Gerald E. Stoica, Angera Kuo, Ciaran Powers, Emma T. Bowden, Elaine Buchert Sale, Anna T. Riegel, Anton Wellstein, Midkine Binds to Anaplastic Lymphoma Kinase (ALK) and Acts as a Growth Factor for Different Cell Types Journal of Biological Chemistry. ,vol. 277, pp. 35990- 35998 ,(2002) , 10.1074/JBC.M205749200
Young Lim Choi, Ruri Kaneda, Tomoaki Wada, Shin-ichiro Fujiwara, Manabu Soda, Hideki Watanabe, Kentaro Kurashina, Hisashi Hatanaka, Munehiro Enomoto, Shuji Takada, Yoshihiro Yamashita, Hiroyuki Mano, None, Identification of a constitutively active mutant of JAK3 by retroviral expression screening. Leukemia Research. ,vol. 31, pp. 203- 209 ,(2007) , 10.1016/J.LEUKRES.2006.05.006
Ruibao Ren, Mechanisms of BCR-ABL in the pathogenesis of chronic myelogenous leukaemia. Nature Reviews Cancer. ,vol. 5, pp. 172- 183 ,(2005) , 10.1038/NRC1567
A. V. Galkin, J. S. Melnick, S. Kim, T. L. Hood, N. Li, L. Li, G. Xia, R. Steensma, G. Chopiuk, J. Jiang, Y. Wan, P. Ding, Y. Liu, F. Sun, P. G. Schultz, N. S. Gray, M. Warmuth, Identification of NVP-TAE684, a potent, selective, and efficacious inhibitor of NPM-ALK Proceedings of the National Academy of Sciences of the United States of America. ,vol. 104, pp. 270- 275 ,(2007) , 10.1073/PNAS.0609412103
Scott A. Tomlins, Bharathi Laxman, Saravana M. Dhanasekaran, Beth E. Helgeson, Xuhong Cao, David S. Morris, Anjana Menon, Xiaojun Jing, Qi Cao, Bo Han, Jindan Yu, Lei Wang, James E. Montie, Mark A. Rubin, Kenneth J. Pienta, Diane Roulston, Rajal B. Shah, Sooryanarayana Varambally, Rohit Mehra, Arul M. Chinnaiyan, Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer Nature. ,vol. 448, pp. 595- 599 ,(2007) , 10.1038/NATURE06024
Toshinori Iwahara, Jiro Fujimoto, Duanzhi Wen, Rod Cupples, Nathan Bucay, Tsutomu Arakawa, Shigeo Mori, Barry Ratzkin, Tadashi Yamamoto, Molecular Characterization of ALK, a Receptor Tyrosine Kinase Expressed Specifically in the Nervous System Oncogene. ,vol. 14, pp. 439- 449 ,(1997) , 10.1038/SJ.ONC.1200849