TLR2 antagonistic antibody and use thereof
作者： Guangxun Meng , Hermann Wagner , Carsten Juergen Kirschning
DOI:
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摘要: The present invention is directed to a cross-reactive antibody, which specifically inhibits or blocks the mammalian Toll-like receptor 2 (TLR2)-mediated immune cell activation. further an isolated nucleic acid vector coding for variable regions of heavy and/or light chain said antibody. It providing pharmaceutical composition comprising and use in prevention treatment inflammatory processes any other process induced by bacterial infection, trauma, chronic inflammation, bacteriaemia sepsis.
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