Anti-apolipoprotein A-1 IgG in patients with myocardial infarction promotes inflammation through TLR2/CD14 complex.
作者： S. Pagano , N. Satta , D. Werling , V. Offord , P. de Moerloose
DOI: 10.1111/J.1365-2796.2012.02530.X
关键词:
摘要: Toll-like receptor (TLR)-mediated vascular inflammation, inducible by - amongst other factors auto-antibodies, is increasingly recognized as a potential mediator of cardiovascular disease. We investigated whether anti-apolipoprotein (Apo)A-1 IgG was associated with pro-inflammatory cytokine profile in myocardial infarction (MI) patients and anti-ApoA-1 elicited response activating TLRs.
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