The Human Autoantibody Response to Apolipoprotein A-I Is Focused on the C-Terminal Helix: A New Rationale for Diagnosis and Treatment of Cardiovascular Disease?

作者: Sabrina Pagano , Hubert Gaertner , Fabrice Cerini , Tiphaine Mannic , Nathalie Satta

DOI: 10.1371/JOURNAL.PONE.0132780

关键词:

摘要: Cardiovascular disease (CVD) is the leading cause of death worldwide and new approaches for both diagnosis treatment are required. Autoantibodies directed against apolipoprotein A-I (ApoA-I) represent promising biomarkers use in risk stratification CVD may also play a direct role pathogenesis.

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