Guidance for laboratories performing molecular pathology for cancer patients.

摘要: Molecular testing is becoming an important part of the diagnosis any patient with cancer. The challenge to laboratories meet this need, using reliable methods and processes ensure that patients receive a timely accurate report on which their treatment will be based. aim paper provide minimum requirements for management molecular pathology laboratories. This general guidance should augmented by specific available different tumour types tests. Preanalytical considerations are important, careful consideration way in specimens obtained reach laboratory necessary. Sample receipt handling follow standard operating procedures, but some alterations may necessary if performed, instance control tissue fixation. DNA RNA extraction can standardised checked quality quantity output regular basis. choice analytical method(s) depends clinical requirements, desired turnaround time, expertise available. Internal control, internal audit whole process, accreditation, continual participation external assessment schemes prerequisites delivery service. A accurately convey information clinician needs treat sufficient allow correct interpretation result. developing rapidly, further detailed evidence-based recommendations required many topics covered here.