Relationships Between TCF7L2 Genetic Polymorphisms and Polycystic Ovary Syndrome Risk: A Meta-Analysis
作者： Wen-Jing Shen , Tian-Ren Li , Yan-Jie Hu , Hong-Bo Liu , Min Song
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摘要: Abstract Objective: This meta-analysis was performed to evaluate the relationships between genetic polymorphisms in TCF7L2 gene and polycystic ovary syndrome (PCOS) risk. Methods: The PubMed, Centralised Information Service for Complementary Medicine (CISCOM), Cumulative Index Nursing Allied Health Literature (CINAHL), Web of Science, Google Scholar, EBSCO, Cochrane Library, Common Biorepository Model (CBM) databases were searched relevant articles published before November 1st, 2013, without language restrictions. Meta-analysis conducted using STATA 12.0 software. evaluated by calculating pooled odds ratios (ORs) their 95% confidence intervals (CIs). Seven case–control studies with a total 2458 PCOS patients 5109 healthy subjects' met our inclusion criteria qualitative data analysis. Two common (rs7903146 C→T rs12255372 G→T) assessed. Results: results suggested that ...
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