作者: Gillian H Lim , Tara Harris , Shalini Desai , Natasha S Crowcroft , Tony Mazzulli
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摘要: Countries of the Americas have been working towards rubella elimination since 2003 and endemic virus transmission appears to interrupted 2009. To contribute monitoring elimination, we assessed seroprevalence among prenatal screening tests performed in Ontario. Specimens received for serologic testing at Public Health Ontario Laboratory, provincial reference laboratory, between 2006 2010 were analyzed. A patient-based dataset was created using all occurring 15–49 year-old females, where indicated. Multiple assigned same patient on basis health card number, name date birth. Only unique least nine months apart included. SAS version 9.2 used analysis. Between 2010, identified 459,963 women who underwent 551,160 rubella. Of these, 81.6%, 17.1% 1.4% had one, two three or more respectively. Rubella immunity remained stable approximately 90% overall; proportion susceptible 4.4%. Additionally, 0.6% initially subsequently developed immunity. Across province, susceptibility highest north declined with increasing age (p < 0.0001). Among multiple tests, as number years increased (p < .0001). Based first test, younger (4.2% 15–19 year-olds) significantly likely develop if previously supports goals population this group is relatively high. Higher young living highlights an opportunity greater focus identification immunization these groups.