Hemoglobin switch in the newborn: a flow cytometry analysis.

作者: Ilana Amoyal , Eitan Fibach

DOI: 10.1159/000096973

关键词:

摘要: Background: Hemoglobin (Hb) production switches upon birth from fetal Hb (HbF) to adult Hbs. HbF is reactivated in sickle cell anemia and β-thalassemia, where increased H

参考文章(24)
L Margolte, P J Burke, W R Bell, T K Belding, S H Boyer, A N Noyes, Variations in the frequency of fetal hemoglobin-bearing erythrocytes (F-cells) in well adults, pregnant women, and adult leukemics. The Johns Hopkins medical journal. ,vol. 137, pp. 105- 115 ,(1975)
S.D.V. Weller, John Apley, AlanB. Raper, MALFORMATIONS ASSOCIATED WITH PRECOCIOUS SYNTHESIS OF ADULT HÆMOGLOBIN The Lancet. ,vol. 287, pp. 777- 779 ,(1966) , 10.1016/S0140-6736(66)91858-7
S Takegawa, M Brice, G Stamatoyannopoulos, T Papayannopoulou, Only adult hemoglobin is produced in fetal nonerythroid x MEL cell hybrids. Blood. ,vol. 68, pp. 1384- 1388 ,(1986) , 10.1182/BLOOD.V68.6.1384.1384
Thalia Papayannopoulou, H. Franklin Bunn, George Stamatoyannopoulos, Cellular distribution of hemoglobin F in a clonal hemopoietic stem-cell disorder. The New England Journal of Medicine. ,vol. 298, pp. 72- 75 ,(1978) , 10.1056/NEJM197801122980203
Marcia C. Willing, Arthur W. Nienhuis, W. French Anderson, Selective activation of human β - but not γ -globin gene in human fibroblast × mouse erythroleukaemia cell hybrids Nature. ,vol. 277, pp. 534- 538 ,(1979) , 10.1038/277534A0
D. J. Weatherall, J. A. Edwards, W. T. Donohoe, Haemoglobin and red cell enzyme changes in juvenile myeloid leukaemia. BMJ. ,vol. 1, pp. 679- 681 ,(1968) , 10.1136/BMJ.1.5593.679
M Haghshenass, F Ismail-Beigi, J B Clegg, D J Weatherall, Mild sickle-cell anaemia in Iran associated with high levels of fetal haemoglobin. Journal of Medical Genetics. ,vol. 14, pp. 168- 171 ,(1977) , 10.1136/JMG.14.3.168
VERNON M. INGRAM, Embryonic Red Blood Cell Formation Nature. ,vol. 235, pp. 338- 339 ,(1972) , 10.1038/235338A0
T. H. Papayannopoulou, M. Brice, G. Stamatoyannopoulos, Stimulation of fetal hemoglobin synthesis in bone marrow cultures from adult individuals Proceedings of the National Academy of Sciences of the United States of America. ,vol. 73, pp. 2033- 2037 ,(1976) , 10.1073/PNAS.73.6.2033