Prolonged QTc indicates the clinical severity and poor prognosis in patients with isolated left ventricular non-compaction.

摘要: Isolated left ventricular non-compaction (LVNC) is a rare cardiomyopathy that leads to severe clinical complications. This study investigate whether or not prolonged QTc good indicator for evaluating the severity of fibrosis and predicting prognosis LVNC, if native T1 can be used quantify fibrosis. 32 LVNC patients 14 healthy controls with matched age sex were examined by CMR ECG acquire T1, interval, abnormalities. 18 had normal QTc. The mean value controls, was 1096.0 ± 41.5, 1141.98 45.46, 1182.67 42.02 ms, respectively. One-way ANVOA showed significant differences in among three groups (F = 14.9, p < 0.001). In patients, interval significantly correlated LVEF (p 0.003, r 0.51) values 0.015, R −0.47). suggests associated more compacted myocardial fibrosis, cardiac dysfunction, poorer patients. Follow-up data adverse events between 0.036). Prolonged