Nitric oxide in gastrointestinal epithelial cell carcinogenesis: linking inflammation to oncogenesis.

作者: Meeta Jaiswal , Nicholas F. LaRusso , Gregory J. Gores

DOI: 10.1152/AJPGI.2001.281.3.G626

关键词:

摘要: … The consequences of protein damage by NO appear to be … by macrophage iNOS has important antimicrobial functions (6, … H 2 O 2 is detoxified by glutathione peroxidase, a selenium …

参考文章(137)
T R Billiar, B S Taylor, L H Alarcon, Inducible nitric oxide synthase in the liver: regulation and function. Biochemistry. ,vol. 63, pp. 766- 781 ,(1998)
L L Nielsen, D C Maneval, P53 tumor suppressor gene therapy for cancer. Cancer Gene Therapy. ,vol. 5, pp. 52- 63 ,(1998)
F. Laval, D. A. Wink, J. Laval, A discussion of mechanisms of NO genotoxicty: Implication of inhibition of DNA repair proteins Reviews of Physiology Biochemistry and Pharmacology. ,vol. 131, pp. 175- 191 ,(1997) , 10.1007/3-540-61992-5_8
G. Weiss, B. Goossen, W. Doppler, D. Fuchs, K. Pantopoulos, G. Werner-Felmayer, H. Wachter, M.W. Hentze, Translational regulation via iron-responsive elements by the nitric oxide/NO-synthase pathway The EMBO Journal. ,vol. 12, pp. 3651- 3657 ,(1993) , 10.1002/J.1460-2075.1993.TB06039.X
Lindy L. Thomsen, David W. Miles, Role of nitric oxide in tumour progression: lessons from human tumours. Cancer and Metastasis Reviews. ,vol. 17, pp. 107- 118 ,(1998) , 10.1023/A:1005912906436
David A. Geller, Timothy R. Billiar, Molecular biology of nitric oxide synthases Cancer and Metastasis Reviews. ,vol. 17, pp. 7- 23 ,(1998) , 10.1023/A:1005940202801
P Lagadec, H Ohshima, P Lejeune, N Onier, J F Jeannin, D Pinard, Nitric oxide involvement in tumor-induced immunosuppression. Journal of Immunology. ,vol. 152, pp. 5077- 5083 ,(1994)
K C Cheng, D S Cahill, H Kasai, S Nishimura, L A Loeb, 8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G----T and A----C substitutions. Journal of Biological Chemistry. ,vol. 267, pp. 166- 172 ,(1992) , 10.1016/S0021-9258(18)48474-8
C. Nathan, Q.W. Xie, Regulation of biosynthesis of nitric oxide. Journal of Biological Chemistry. ,vol. 269, pp. 13725- 13728 ,(1994) , 10.1016/S0021-9258(17)36703-0