Efficacy of Calcium Phosphate-Based Scaffold Materials on Mineralized and Non-mineralized Tissue Regeneration
作者： Osamu Suzuki , Takahisa Anada , Yukari Shiwaku
DOI: 10.1007/978-981-10-1560-1_10
关键词:
摘要: Calcium phosphate materials have been advocated as useful implantable scaffolds for bone tissue engineering. We reported that synthetic octacalcium (OCP) is capable of enhancing differentiation hard tissue-forming cells including osteoblastic cells, osteoclast precursor and odontoblastic cells. The mesenchymal stem promoted to form new in the presence OCP with atelo-collagen vivo condition. stimulatory capacity conduct increases copresence amorphous calcium (ACP). Physical chemical analyses suggested bioactivity such hydroxyapatite (HA) phases induced a result progressive change property these during hydrolysis into HA under physiological environment. composite composed natural polymers are repairing not only mineralized tissues but also non-mineralized tissue. OCP-based responses will be summarized.
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