RECIST 1.1 in NSCLC Patients With EGFR Mutations Treated With EGFR Tyrosine Kinase Inhibitors: Comparison With RECIST 1.0
作者： Mizuki Nishino , Stephanie Cardarella , David M. Jackman , Nikhil H. Ramaiya , Michael S. Rabin
DOI: 10.2214/AJR.12.9668
关键词:
摘要: OBJECTIVE. Response Evaluation Criteria in Solid Tumors (RECIST) 1.1 has been rapidly accepted clinical trials as a standard measure to assess tumor response therapy and is expected improve assessment, especially genomically defined patients. The impact of RECIST was compared with 1.0 non–small cell lung cancer (NSCLC) patients sensitizing epidermal growth factor receptor (EGFR) mutations treated EGFR tyrosine kinase inhibitors. MATERIALS AND METHODS. Seventy advanced NSCLC harboring first-line inhibitor were retrospectively studied. Tumor measurements assessment performed using 1.1. number target lesions, the percentage change at initial follow-up, best response, time progression between 1.0. RESULTS. lesions identified significantly lower wi...
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