Eradication therapy for Pseudomonas aeruginosa colonization episodes in cystic fibrosis patients not chronically colonized by P. aeruginosa

摘要: Abstract Pseudomonas aeruginosa ( Pa ) is one of the most common and clinically important pathogens in patients with cystic fibrosis (CF). Chronic colonization CF associated increased morbidity mortality. strains causing early infection are usually antibiotic sensitive have low bacterial density airways. As a result, treatment strategy has shifted from suppressive therapy chronically colonized by to attempts at eradication as soon detected. In literature, different regimens been studied. However, optimal regimen duration not yet determined. this article, an overview on natural history given. Moreover, results trials directions for future research discussed.