Optimization of High Resolution Melting Analysis for Detection of KRAS Gene Mutations
作者: Ashna Darbandy
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摘要: Background: Mutations of the KRAS oncogene occur in a variety types human tumors. By assessing mutation status KRAS, clinicians can predict patient response to anti-EGFR therapy such as c ...
Derek J. Jonker, Chris J. O'Callaghan, Christos S. Karapetis, John R. Zalcberg, Dongsheng Tu, Heather-Jane Au, Scott R. Berry, Marianne Krahn, Timothy Price, R. John Simes, Niall C. Tebbutt, Guy van Hazel, Rafal Wierzbicki, Christiane Langer, Malcolm J. Moore, Cetuximab for the Treatment of Colorectal CancerThe New England Journal of Medicine. ,vol. 357, pp. 2040- 2048 ,(2007) , 10.1056/NEJMOA071834