Replacing PCR with COLD-PCR enriches variant DNA sequences and redefines the sensitivity of genetic testing.
作者： Jin Li , Lilin Wang , Harvey Mamon , Matthew H Kulke , Ross Berbeco
DOI: 10.1038/NM1708
关键词:
摘要: … initial DNA amplification step for genetic testing. However, a key … in their ability to identify subtle genetic changes that can have a … of PCR-based genetic testing, including applications in …
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