Phosphorylation of WAVE1 regulates actin polymerization and dendritic spine morphology
作者： Yong Kim , Jee Young Sung , Ilaria Ceglia , Ko-Woon Lee , Jung-Hyuck Ahn
DOI: 10.1038/NATURE04976
关键词:
摘要: … Cdk5 inhibits its ability to regulate Arp2/3 complex-dependent actin polymerization. Loss of … the filamentous actin cytoskeleton, and thus in the regulation of dendritic spine morphology. …
nature.com
harvard.edu
postech.ac.kr
researchgate.net 参考文章(25)
Akinori Nishi, Gretchen L. Snyder, Paul Greengard, Bidirectional Regulation of DARPP-32 Phosphorylation by Dopamine The Journal of Neuroscience. ,vol. 17, pp. 8147- 8155 ,(1997) , 10.1523/JNEUROSCI.17-21-08147.1997
Gentry N. Patrick, Lawrence Zukerberg, Margareta Nikolic, Suzanne de la Monte, Pieter Dikkes, Li-Huei Tsai, Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration Nature. ,vol. 402, pp. 615- 622 ,(1999) , 10.1038/45159
James A. Bibb, Jingshan Chen, Jane R. Taylor, Per Svenningsson, Akinori Nishi, Gretchen L. Snyder, Zhen Yan, Zachary K. Sagawa, Charles C. Ouimet, Angus C. Nairn, Eric J. Nestler, Paul Greengard, Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5 Nature. ,vol. 410, pp. 376- 380 ,(2001) , 10.1038/35066591
James A. Bibb, Gretchen L. Snyder, Akinori Nishi, Zhen Yan, Laurent Meijer, Allen A. Fienberg, Li-Huei Tsai, Young T. Kwon, Jean-Antoine Girault, Andrew J. Czernik, Richard L. Huganir, Hugh C. Hemmings, Angus C. Nairn, Paul Greengard, Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons Nature. ,vol. 402, pp. 669- 671 ,(1999) , 10.1038/45251
Taro Saito, Reiko Onuki, Yuichi Fujita, Gen-ichi Kusakawa, Koichi Ishiguro, James A. Bibb, Takeo Kishimoto, Shin-ichi Hisanaga, Developmental Regulation of the Proteolysis of the p35 Cyclin-Dependent Kinase 5 Activator by Phosphorylation The Journal of Neuroscience. ,vol. 23, pp. 1189- 1197 ,(2003) , 10.1523/JNEUROSCI.23-04-01189.2003
Ann Y. Nakayama, Matthew B. Harms, Liqun Luo, Small GTPases Rac and Rho in the Maintenance of Dendritic Spines and Branches in Hippocampal Pyramidal Neurons The Journal of Neuroscience. ,vol. 20, pp. 5329- 5338 ,(2000) , 10.1523/JNEUROSCI.20-14-05329.2000
H. Miki, T. Takenawa, WASP and WAVE family proteins: key molecules for rapid rearrangement of cortical actin filaments and cell movement Journal of Cell Science. ,vol. 114, pp. 1801- 1809 ,(2001) , 10.1242/JCS.114.10.1801
Theresia E.B. Stradal, Klemens Rottner, Andrea Disanza, Stefano Confalonieri, Metello Innocenti, Giorgio Scita, Regulation of actin dynamics by WASP and WAVE family proteins. Trends in Cell Biology. ,vol. 14, pp. 303- 311 ,(2004) , 10.1016/J.TCB.2004.04.007
K.-W. Lee, Y. Kim, A. M. Kim, K. Helmin, A. C. Nairn, P. Greengard, Cocaine-induced dendritic spine formation in D1 and D2 dopamine receptor-containing medium spiny neurons in nucleus accumbens. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 103, pp. 3399- 3404 ,(2006) , 10.1073/PNAS.0511244103
Liqun Luo, Takao K. Hensch, Larry Ackerman, Sandra Barbel, Lily Y. Jan, Yuh Nung Jan, Differential effects of the Rac GTPase on Purkinje cell axons and dendritic trunks and spines Nature. ,vol. 379, pp. 837- 840 ,(1996) , 10.1038/379837A0