作者: Patricia Rojas-Ríos , Acaimo González-Reyes
DOI: 10.1002/STEM.1621
关键词:
摘要: Stem cell activity is tightly regulated during development and in adult tissues through the combined action of local systemic effectors. While stem cells their microenvironments are capable sustaining homeostasis normal physiological circumstances, they also provide host with a remarkable plasticity to respond perturbations. Here, we review recent discoveries that shed light on adaptive response niches signals aging, ability modulate signaling upon These characteristics give organs an essential advantage deal injury or pathological conditions. Cells 2014;32:852–859