Concise Review: The Plasticity of Stem Cell Niches: A General Property Behind Tissue Homeostasis and Repair

作者: Patricia Rojas-Ríos , Acaimo González-Reyes

DOI: 10.1002/STEM.1621

关键词:

摘要: Stem cell activity is tightly regulated during development and in adult tissues through the combined action of local systemic effectors. While stem cells their microenvironments are capable sustaining homeostasis normal physiological circumstances, they also provide host with a remarkable plasticity to respond perturbations. Here, we review recent discoveries that shed light on adaptive response niches signals aging, ability modulate signaling upon These characteristics give organs an essential advantage deal injury or pathological conditions. Cells 2014;32:852–859

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