Polymeric alkenoxy amino acid surfactants: IV. Effects of hydrophobic chain length and degree of polymerization of molecular micelles on chiral separation of β‐blockers
作者： Syed Asad Ali Rizvi , Shahab A. Shamsi
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摘要: Four alkenoxy leucine-based surfactants with C 8 -C 1 chains containing a terminal double bond, and one chain surfactant triple bond are synthesized characterized in monomeric polymeric forms. These pseudophases then utilized to study the influence of length DP for enantioseparations seven β-blockers MEKC. Variations concentration showed significant effects on chiral resolution (R s ) efficiency (N). A relatively large elution range combined highest polarity aggregation number (A) but lowest retention time, partial specific volume, optical rotation generated -polymeric results simultaneous enantioseparation all p-blockers higher N R . In particular, highly hydrophobic better resolved shorter hydrocarbon even at concentration, which is unachievable longer surfactant. On other hand, polymer derived from -triple provided smaller value compared -double However, still achievable enhanced analysis time. addition, effect polymerization evaluated by polymerizing five times their respective CMCs 100 mM equivalent monomer concentrations. Polymerization (C 9 double-bonded values same two polymerized mM.
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