Angiogenesis in gliomas
作者： Agnieszka Lebelt , Janusz Dziecioł , Katarzyna Guzińska-Ustymowicz , Dorota Lemancewicz , Lech Zimnoch
DOI: 10.2478/V10042-008-0009-4
关键词:
摘要: Brain gliomas are characterized by invasive growth and neovascularisation potential. Angiogenesis plays a major role in the progression of its determination has great prognostic value. The aim study was to assess vascularisation chosen brain estimate how it is correlated with tumour histological type, malignancy grade, location size, age sex patients. Tumour analysis based on microvascular proliferation (MVP) microvessel density (MVD). Microvascular measured immunohistochemical methods using mouse monoclonal antibodies detect cell antigens. following were used Ki-67 PCNA (DAKO). Identification vessels performed CD31 antibody anti-human von Willebrand factor highest observed multiform glioblastomas lowest oligodendrogliomas. Significant correlation between grade.
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