Effect of genetic variation in the organic cation transporter 1 (OCT1) on metformin action.

作者: Yan Shu , Steven A. Sheardown , Chaline Brown , Ryan P. Owen , Shuzhong Zhang

DOI: 10.1172/JCI30558

关键词:

摘要: Metformin is among the most widely prescribed drugs for the treatment of type 2 diabetes. Organic cation transporter 1 (OCT1) plays a role in the hepatic uptake of metformin, but its role …

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