Methylated DNA as Cancer Biomarkers in Circulation

Ana Luiza Bomfim Longo, Marianna M. Rettori, Ana Carolina de Carvalho, Luiz Paulo Kowalski, Andre Lopes Carvalho, Andre Luiz Vettore, Evaluation of the methylation profile of exfoliated cell samples from patients with head and neck squamous cell carcinoma Head and Neck-journal for The Sciences and Specialties of The Head and Neck. ,vol. 36, pp. 631- 637 ,(2014) , 10.1002/HED.23345

Terence W. Friedlander, Vy T. Ngo, Huan Dong, Gayatri Premasekharan, Vivian Weinberg, Shaun Doty, Qiang Zhao, Elizabeth G. Gilbert, Charles J. Ryan, Wen-Tien Chen, Pamela L. Paris, Detection and characterization of invasive circulating tumor cells derived from men with metastatic castration-resistant prostate cancer. International Journal of Cancer. ,vol. 134, pp. 2284- 2293 ,(2014) , 10.1002/IJC.28561

Siane Lopes Bittencourt Rosas, Wayne Koch, Maria da Gloria da Costa Carvalho, Li Wu, Joseph Califano, William Westra, Jin Jen, David Sidransky, None, Promoter Hypermethylation Patterns of p16, O6-Methylguanine-DNA-methyltransferase, and Death-associated Protein Kinase in Tumors and Saliva of Head and Neck Cancer Patients Cancer Research. ,vol. 61, pp. 939- 942 ,(2001)

Manel Esteller, David Sidransky, Montserrat Sanchez-Cespedes, Stephen B. Baylin, Rafael Rosell, James G. Herman, Detection of Aberrant Promoter Hypermethylation of Tumor Suppressor Genes in Serum DNA from Non-Small Cell Lung Cancer Patients Cancer Research. ,vol. 59, pp. 67- 70 ,(1999)

Ivy HN Wong, YM Dennis Lo, Jun Zhang, Choong-Tsek Liew, Margaret HL Ng, Nathalie Wong, Paul BS Lai, Wan Y Lau, N Magnus Hjelm, Philip J Johnson, None, Detection of Aberrant p16 Methylation in the Plasma and Serum of Liver Cancer Patients Cancer Research. ,vol. 59, pp. 71- 73 ,(1999)

Sameer Mirza, Gayatri Sharma, Rajinder Parshad, Anurag Srivastava, Siddartha Datta Gupta, Ranju Ralhan, Clinical Significance of Promoter Hypermethylation of ERβ and RARβ2 in Tumor and Serum DNA in Indian Breast Cancer Patients Annals of Surgical Oncology. ,vol. 19, pp. 3107- 3115 ,(2012) , 10.1245/S10434-012-2323-5

Noriko Fujita, Takahiro Nakayama, Noriaki Yamamoto, Seung Jin Kim, Kenzo Shimazu, Atsushi Shimomura, Naomi Maruyama, Koji Morimoto, Yasuhiro Tamaki, Shinzaburo Noguchi, Methylated DNA and total DNA in serum detected by one-step methylation-specific PCR is predictive of poor prognosis for breast cancer patients. Oncology. ,vol. 83, pp. 273- 282 ,(2012) , 10.1159/000342083

Thomas E. Liggett, Anatoliy Melnikov, Qilong Yi, Charles Replogle, Wei Hu, Jacob Rotmensch, Aparna Kamat, Anil K. Sood, Victor Levenson, Distinctive DNA methylation patterns of cell-free plasma DNA in women with malignant ovarian tumors. Gynecologic Oncology. ,vol. 120, pp. 113- 120 ,(2011) , 10.1016/J.YGYNO.2010.09.019

Tuangtong Pobsook, Keskanya Subbalekha, Phakdee Sannikorn, Apiwat Mutirangura, Improved measurement of LINE-1 sequence methylation for cancer detection. Clinica Chimica Acta. ,vol. 412, pp. 314- 321 ,(2011) , 10.1016/J.CCA.2010.10.030

K L Mahon, , W Qu, J Devaney, C Paul, L Castillo, R J Wykes, M D Chatfield, M J Boyer, M R Stockler, G Marx, H Gurney, G Mallesara, P L Molloy, L G Horvath, S J Clark, Methylated Glutathione S-transferase 1 (mGSTP1) is a potential plasma free DNA epigenetic marker of prognosis and response to chemotherapy in castrate-resistant prostate cancer British Journal of Cancer. ,vol. 111, pp. 1802- 1809 ,(2014) , 10.1038/BJC.2014.463