A comparison of nutritional and genetic blocks in the synthesis of purines by yeasts, molds and bacteria
作者： Herman Friedman , Albert G. Moat
DOI: 10.1016/0003-9861(58)90323-0
关键词:
摘要: Abstract 5-Aminoimidazole riboside and inosine are accumulated by biotin-deficient yeast. The addition of aspartic acid prevents accumulation these intermediates in the incubation medium. Purine-requiring yeast, neurospora, vibrio strains accumulate 5-aminoimidazole but not inosine. Aspartic fails to prevent accumulation, an indication a genetic block ability organisms metabolize this compound further. relationship biotin purine biosynthesis yeast is discussed light data presented.
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