The antimicrobial potential of 14 natural herbal dentifrices: Results of an in vitro diffusion method study

摘要: ABSTRACT Background Increasing numbers of Americans are using natural herbal products for general and oral health care. Few these products, however, have undergone rigorous testing, as evidenced by the limited amount information on their safety efficacy in literature. The authors conducted an vitro study to evaluate antimicrobial potential 14 dentifrices. Methods used a diffusion method effectiveness dentifrices against four microorganisms: Streptococcus mutans, sanguis, Actinomyces viscosus Candida albicans . Colgate Total (Colgate-Palmolive, New York City) sterile pyrogen-free water served positive negative controls, respectively. tested at full strength 1:1 dilution. They measured zones inhibition 24 48 hours Results Six were effective inhibiting growth all microorganisms. control produced significantly sized with microorganisms, while no observable zones. larger A. than did control. inhibitory C. strength, but dilution, only three had such effect. One dentifrice microbial around over samples, indicating possible contamination toothpaste. Only one showed consistent activity Conclusions variation among indicates that more research is needed validate claims. Clinical Implications This provides practitioners insight into claims dentifrices' effects.