Release of zinc from the brain of El (epilepsy) mice during seizure induction
作者： Atsushi Takeda , Tomoyuki Hanajima , Hiromi Ijiro , Atsushi Ishige , Susumu Iizuka
DOI: 10.1016/S0006-8993(99)01358-X
关键词:
摘要: Brain distribution after i.v. injection of 65ZnCl2 into El mice, an animal model genetically determined epilepsy, was studied by autoradiography to study the utilization zinc in brain. The 65Zn brain mice 6 days almost same as that ddY (normal) suggesting uptake is normal. To movement course seizure induction, concentrations seizure-afflicted and untreated control were compared 20 injection. concentration seized overall lower than mice; decreased notably piriform cortex amygdaloid nuclei complex during convulsion. These results suggest release from mouse enhanced decrease actively functioning may be associated with increase susceptibility mouse.
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