Circulating Endothelial Cell Count as a Diagnostic Marker for Non–ST-Elevation Acute Coronary Syndromes

作者: Jacques Quilici , Nathalie Banzet , Philippe Paule , Jean-Baptiste Meynard , Murielle Mutin

DOI: 10.1161/01.CIR.0000142295.85740.98

关键词:

摘要: Background— Shedding of endothelial cells from damaged endothelium into the blood occurs in a variety vascular disorders. The purpose this study was to evaluate utility circulating cell (CEC) count as diagnostic marker non–ST-elevation acute coronary syndromes (ACSs). Methods and Results— CEC counts were determined immediately (H0), 4 hours (H4), 8 (H8) after admission 60 patients with documented ACS 40 control no evidence artery disease. A total 32 group had elevated (>3 cells/mL) relation early single-episode chest pain. Patients normal counts. interval between pain episode elevation significantly shorter for than troponin I. No correlation found 2 markers. Interestingly, subgroup initially I levels high counts, thus allowing diagnosis in...

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