Janus kinase inhibitors and uses thereof

摘要: The present invention provides kinase inhibitors, such as compounds of Formula (I) and (II). may covalently or non-covalently bind a (e.g., Janus 3 (JAK3)). Also provided are pharmaceutical compositions, kits, methods, uses that involve the for reducing activity and/or treating preventing condition associated with aberrant proliferative disease, inflammatory disorder, autoimmune painful condition, viral infection). (II)