Safety of subcutaneous immunotherapy with inhalant allergen extracts: a single-center 30-year experience from Turkey
作者： Ozgur Kartal , Mustafa Gulec , Zafer Caliskaner , Ugur Musabak , Osman Sener
DOI: 10.3109/08923973.2015.1027918
关键词:
摘要: AbstractContext: Although subcutaneous allergen immunotherapy (SCIT) is effective in allergic rhinitis (AR) and asthma, it carries a risk of local systemic adverse reactions.Objective: The aim this study was to evaluate the rates clinical characteristics reactions (LR SR), identify their relation demographic features, extracts diagnosis.Materials methods: This analyzed administration SCIT from 1983 2013; involving 1816 patients affected by asthma and/or AR.Results: SR were 0.078% per injection 9% patient. According World Allergy Organization 2010 grading system, 91 grade 1 (44%), 67 2 (32.3%), 33 3 (16%) 16 4 (7.7%) seen. There no fatal outcome any SRs. Risk factors for included: aluminium-adsorbed extract, pollen-containing vaccines, large LR recurrent (≥2) LRs. total 0.0...
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