Optoacoustic technique for noninvasive monitoring of blood oxygenation: a feasibility study.

作者: Rinat O. Esenaliev , Irina V. Larina , Kirill V. Larin , Donald J. Deyo , Massoud Motamedi

DOI: 10.1364/AO.41.004722

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摘要: Replacement of invasive monitoring cerebral venous oxygenation with noninvasive techniques offers great promise in the management life-threatening neurologic illnesses including traumatic brain injury. We developed and built an optoacoustic system to noninvasively monitor oxygenation; includes a nanosecond Nd:YAG laser specially designed probe. tested vitro sheep blood experimentally varied oxygenation. Our results demonstrated that (1) amplitude temporal profile waves increase range from 24% 92%, (2) signals can be detected despite optical acoustic attenuation by thick bone, (3) is capable real-time continuous measurements. These suggest technique technically feasible for continuous,

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