Issues in the analysis of oligonucleotide tiling microarrays for transcript mapping

摘要: Traditional microarrays use probes complementary to known genes quantitate the differential gene expression between two or more conditions. Genomic tiling microarray experiments differ in that span a genomic region at regular intervals are used detect presence absence of transcription. This difference means same sets biases and methods for addressing them unlikely be relevant both types experiment. We introduce informatics challenges arising analysis as open problems scientific community present initial approaches this nascent technology.