Whole blood concentrations of chloroquine and desethylchloroquine during and after treatment of adult patients infected with Plasmodium vivax, P. ovale or P. malariae.
作者： Lars Rombo , Anders Björkman , Emilia Sego , Örjan Ericsson
DOI: 10.1016/0035-9203(86)90380-9
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摘要: Abstract Whole blood concentrations of chloroquine and desethychloroquine were determined during after treatment 15 adult patients infected with P. vivax, ovale or malariae. The median remained practically unchanged in samples drawn three hours initiation immediately before the next dose chloroquine. Concentrations above 1·0 μmol/litre for at least four days. calculated sum desethylchloroquine was seven These are regarded as sufficient malariae infections.
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