作者: Randy L. King , Bruce A. Herman , Subha Maruvada , Keith A. Wear , Gerald R. Harris
DOI: 10.1063/1.2744296
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摘要: The field of high intensity focused ultrasound (HIFU) is developing rapidly. For basic research, quality control, and regulatory assessment a reusable phantom that has both thermal acoustic properties close to soft tissue critical. A hydrogel‐based mimicking material (TMM) been developed shows promise for such phantom. attenuation, speed sound, B/A, diffusivity conductivity, as well the cavitation threshold, were measured found mimic published values tissue. attenuation 0.53f1.04 from 1 MHz 8 MHz, sound 1565 m/s tissue‐like image quality, indicate usefulness TMM imaging applications. These along with conductivity 0.58 W/m‐ °C, 0.15 (mm2)/s, ability withstand temperatures above 95 °C make this appropriate HIFU also allows embedding thermocouples formation wall‐less vessels do not deteriorate result continuous flow blood fluids through material. Tissue characteristics are strongly dependent on fabrication technique, care must be taken achieve reproducible results. Note: This research was supported by Defense Advanced Research Projects Agency (DARPA).