作者: Nasim Paryab , Duane S. Cronin , Pearl Lee-Sullivan
DOI: 10.1002/CNM.2605
关键词:
摘要: Stent angioplasty or stenting is the standard noninvasive therapy method to address narrowing of arteries and restore blood flow. Although drug-eluting stents have resolved immediate restenosis (i.e., re-narrowing stented arteries), late in-stent continues provide challenges for this treatment. One way through use biodegradable stents, such as helical stent configuration investigated in work, which may reduce risk restenosis. The focus study was analyze mechanical performance expansion a polymeric stent, applied coronary artery. Experimental testing device presents many costly. Hence, initial evaluation using numerical methods provides an opportunity investigate some aspects detail. Existing modeling originally developed metallic wire mesh simulations were used response 5 coil stent. The include: prescribed displacement, uniform balloon expansion. It determined that only could capture important non-uniform expansion, foreshortening change pitch observed experimental tests, since mechanism different compared traditional stents. More important, it found limited by (dog boning) unique progressive proposed mitigate issue. Finally, models within artery containing plaque. predicted interaction with decreased free An plaque demonstrated higher stresses vicinity modest outside region, are desirable terms reducing occurrence techniques work allowed novel method. model most accurately predict geometric effects and, although particular geometry relatively low zone making promising approach