Role of Postreplicative DNA Mismatch Repair in the Cytotoxic Action of Thioguanine

作者: P. F. Swann , T. R. Waters , D. C. Moulton , Y.-Z. Xu , Q. Zheng

DOI: 10.1126/SCIENCE.273.5278.1109

关键词:

摘要: It is proposed here that the delayed cytotoxicity of thioguanine involves the postreplicative DNA mismatch repair system. After incorporation into DNA, the thioguanine is chemically …

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