Influence of geography, seasons and pedology on chemical composition and anti-inflammatory activities of essential oils from Lippia multiflora Mold leaves.
作者： Lêniféré Chantal Soro , Sylvie Munier , Yves Pelissier , Lidwine Grosmaire , Rickey Yada
DOI: 10.1016/J.JEP.2016.10.047
关键词:
摘要: Abstract Ethnopharmacological relevance Lippia multiflora is a plant with nutritional and pharmaco-therapeutic properties that native to central occidental Africa. The potential effects of plants on health are associated their chemical composition. Therefore, the present study aimed identify variations in essential oils as function geographic origin time annual harvest determine optimal profiles for ethno-pharmacotherapeutic applications. Materials methods Experimental were cultivated at Abidjan (LPA), Toumodi (LPT) Bondoukou (LPB). Natural seeds sourced produce standardized over period six months. Standard (n=40) re-introduced into natural plots, 12 months leaves sampled monthly fashion. Essentials (n=36) then extracted from these samples by hydro-distillation according European Pharmacopoeia qualitatively quantitatively analyzed using GC/FID GC/MS. These data Principal Component Analysis (PCA). Anti-inflammatory also assessed against activated macrophages vitro. Results results indicated oil yields vary location where cultivated. One chemotype corresponded LPA LPT sites one LPB site. Statistical analysis evolution three year allowed assessment composition subsequent choice ethnopharmacological activity apparently correlated origins plants. Conclusion was maximum yield pharmacological compounds most interest health.
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