Comparison of the Uniaxial Tensile Strength, Elasticity and Thermal Stability between Glutaraldehyde and Glutaraldehyde with Solvent Fixation in Xenograft Cardiovascular Tissue

摘要: Background: With the advances of cardiac surgery, demand for an artificial prosthesis has increased, and this led to development utilization diverse alternative materials. We conducted research improve by examining changes physical qualities, pressure related tensile strength, change in elasticity thermostability a xenograft valve (porcine) pericardium (bovine, porcine) based on type fixation liquid we used. Material Method: The valves were assigned into three groups: untreated group, fixed with glutaraldehyde (GA) group GA＋ solvent such as ethanol etc. group. surgeons carried out each group"s activities. Each uniaxial tension was measured compared. Thermostability testing compared between bovine porcine GA GA＋solvent Result: On activity test surgeon"s hand, no significant difference groups sensed palpation. For suture tension, slightly firmer than low concentration In general, circumferential aortic pulmonary better that There (p＞0.05). Bovine also showed When comparing experiment, tended be stronger most higher (porcine valve, pericardium). pericardium, both had sudden shrinking point at 80°C (bovine pericardium: p=0.057, p=0.227). Conclusion: fixing prosthetic devices GA, adding did not cause loss pressure-tension, tension-elasticity thermostability. addition, more functional solvents or cleansers should developed developing xenografts.