Recidivism Is the Leading Cause of Death Among Intravenous Drug Users Who Underwent Cardiac Surgery for Infective Endocarditis

摘要: The proportional incidence of intravenous drug use (IVDU)-associated infective endocarditis (IE) cases requiring surgery has increased significantly, mirroring the national opioid crisis. Recidivism is common but its impact on postoperative outcomes unclear. We aimed to evaluate short- and mid-term associated with recidivism in this population. retrospectively reviewed 180 consecutive patients (54 IVDU 126 non-IVDU) surgically treated for IE from 2011 2016. institutional database was linked Connecticut Department Public Health Death Index capture statewide long-term mortality causes death. Regression models were fitted association between status perioperative adverse events, survival, younger had fewer comorbidities. Diabetes, hypertension, peripheral vascular disease, previous coronary artery bypass graft less frequently present compared non-IVDU (P