Production and use of modified cystatins

作者: Masahiro Ogawa , Soichiro Nakamura , Shuryo Nakai

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摘要: Cystatins that have been modified by glycosylation in order to enhance stability and activity are disclosed, as methods of making such cystatins using inhibit proteolysis.

参考文章(12)
S. Nakamura, H. Takasaki, K. Kobayashi, A. Kato, Hyperglycosylation of hen egg white lysozyme in yeast. Journal of Biological Chemistry. ,vol. 268, pp. 12706- 12712 ,(1993) , 10.1016/S0021-9258(18)31445-5
Soichiro Nakamura, Masahiro Ogawa, Shuryo Nakai, Effects of polymannosylation of recombinant cystatin C in yeast on its stability and activity Journal of Agricultural and Food Chemistry. ,vol. 46, pp. 2882- 2887 ,(1998) , 10.1021/JF9801217
M. Yamashita, S. Konagaya, Molecular cloning and gene expression of chum salmon cystatin. Journal of Biochemistry. ,vol. 120, pp. 483- 487 ,(1996) , 10.1093/OXFORDJOURNALS.JBCHEM.A021438
Soichiro Nakamura, Masahiro Ogawa, Masayoshi Saito, Shuryo Nakai, Application of polymannosylated cystatin to surimi from roe-herring to prevent gel weakening FEBS Letters. ,vol. 427, pp. 252- 254 ,(1998) , 10.1016/S0014-5793(98)00437-2
Fugen Li, Haejung An, Thomas A. Seymour, C.Samuel Bradford, Michael T Morrissey, George S Bailey, Angela Helmrich, David W Barnes, Molecular cloning, sequence analysis and expression distribution of rainbow trout (Oncorhynchus mykiss) cystatin C Comparative Biochemistry and Physiology B. ,vol. 121, pp. 135- 143 ,(1998) , 10.1016/S0305-0491(98)10074-3
Yuan-Jang Tsai, Geen-Dong Chang, Chang-Jen Huang, Yea-Sha Chang, Fore-Lien Huang, PURIFICATION AND MOLECULAR CLONING OF CARP OVARIAN CYSTATIN Comparative Biochemistry and Physiology B. ,vol. 113, pp. 573- 580 ,(1996) , 10.1016/0305-0491(95)02070-5
Anders Grubb, Henrik Dalboge, Magnus Abrahamson, Ake Lundwall, Recombinant 3-des-OH-cystatin C produced by expression in a procaryotic host cell ,(1992)