Lower socioeconomic status and shorter survival following HIV infection

摘要: We studied the association between socioeconomic status and survival in a prospective study of 364 HIV-infected homosexual men who were recruited during 1982-84. The participants divided by annual income; those earning above Canadian $10,000 (high-income; n = 274) below (low-income; 90) at recruitment. latter threshold closely approximated to poverty level for this population. Low income significantly younger than high but groups similar with respect baseline CD4 counts, subsequent use anti-retrovirals prophylaxis against Pneumocystis carinii pneumonia (PCP), number visits attended follow-up. Subjects followed median 9.5 years (range 1.8-13.1). By Dec 31, 1993, there 135 deaths yielding cumulative mortality rate mean 45% (SD 4.0) 11.5 years. Men aged 30 or more infection had poorer under (mortality risk ratio 1.56; 95% CI 1.09-2.24; p 0.015), longer was associated higher count earliest seropositive visit. age-adjusted low compared increased 1.63 (95% 1.11-2.40; 0.013). significant death persisted despite adjustment age infection, count, zidovudine, dideoxyinosine, dideoxycytidine, PCP prophylaxis, year infection. cannot attribute our findings loss as result rapid HIV progression because same effect present people provided data before seroconversion. Similarly, are not due differential access care done within context universal health system, two received treatments equally. This finding is consistent lower morbidity observed large populations other diseases.