Sensitivity and specificity of color duplex ultrasound measurement in the estimation of internal carotid artery stenosis: A systematic review and meta-analysis

作者: Afshin S. Jahromi , Claudio S. Cinà , Yan Liu , Catherine M. Clase

DOI: 10.1016/J.JVS.2005.02.044

关键词:

摘要: Background Duplex ultrasound is widely used for the diagnosis of internal carotid artery stenosis. Standard duplex criteria grading stenosis do not exist; thus, we conducted a systematic review and meta-analysis relation between degree by angiography. Methods Data were gathered from Medline January 1966 to 2003, Cochrane Central Register Controlled Trials Database Systematic Reviews, Abstracts Reviews Effects, ACP Journal Club, UpToDate, reference lists, authors' files. Inclusion comparison color results with angiography North American Symptomatic Carotid Endarterectomy Trial method; peer-reviewed publications, ≥10 adults. Results Variables extracted included peak systolic velocity, end diastolic artery/common velocity ratio, sensitivity specificity scanning The Standards Reporting Diagnostic Accuracy (STARD) assess study quality. Sensitivity combined as weighted means using random effects model. threshold ≥130 cm/s associated 98% (95% confidence intervals [CI], 97% 100%) 88% CI, 76% in identification angiographic ≥50%. For ≥70%, ≥200 has 90% 84% 94%) 94% 97%). each threshold, measurement properties vary laboratories, magnitude variation clinically important. heterogeneity observed may be caused differences patients, design, equipment, techniques or training. Conclusions Clinicians need aware limitations when making management decisions.

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