A Bull's Eye for Targeted Lung Cancer Therapy

作者: John D Minna , Adi F Gazdar , Stephen R Sprang , Joachim Herz

DOI: 10.1126/SCIENCE.1099578

关键词:

摘要: The tyrosine kinase inhibitor gefitinib has had mixed results in the treatment of lung cancer. reason is now revealed two papers published here ( Paez et al.) and elsewhere, which receive in-depth discussion a Perspective by Minna al. new studies show that tumors from subset cancer patients with an efficacious response to carry mutations domain EGF receptor. findings should enable early selection those most likely respond well gefitinib.

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