Functional Characterization of the S. cerevisiae Genome by Gene Deletion and Parallel Analysis

作者: Elizabeth A Winzeler , Daniel D Shoemaker , Anna Astromoff , Hong Liang , Keith Anderson

DOI: 10.1126/SCIENCE.285.5429.901

关键词:

摘要: … A total of 6925 Saccharomyces cerevisiae strains were … Of the deleted ORFs, 17 percent were essential for viability in … A lighter gray background indicates the location of chromosomal …

参考文章(35)
J.D. Brown, B.C. Hann, K.F. Medzihradszky, M. Niwa, A.L. Burlingame, P. Walter, Subunits of the Saccharomyces cerevisiae signal recognition particle required for its functional expression. The EMBO Journal. ,vol. 13, pp. 4390- 4400 ,(1994) , 10.1002/J.1460-2075.1994.TB06759.X
Guri Giaever, Daniel D. Shoemaker, Ted W. Jones, Hong Liang, Elizabeth A. Winzeler, Anna Astromoff, Ronald W. Davis, Genomic profiling of drug sensitivities via induced haploinsufficiency. Nature Genetics. ,vol. 21, pp. 278- 283 ,(1999) , 10.1038/6791
Kenneth H. Wolfe, Denis C. Shields, Molecular evidence for an ancient duplication of the entire yeast genome Nature. ,vol. 387, pp. 708- 713 ,(1997) , 10.1038/42711
T. Y.-K. Chow, D. Y. Thomas, J. J. Ash, D. Dignard, Screening and identification of a gene, PSE-1, that affects protein secretion in Saccharomyces cerevisiae Journal of Cell Science. ,vol. 101, pp. 709- 719 ,(1992) , 10.1242/JCS.101.3.709
S Kasahara, H Yamada, T Mio, Y Shiratori, C Miyamoto, T Yabe, T Nakajima, E Ichishima, Y Furuichi, Cloning of the Saccharomyces cerevisiae gene whose overexpression overcomes the effects of HM-1 killer toxin, which inhibits beta-glucan synthesis. Journal of Bacteriology. ,vol. 176, pp. 1488- 1499 ,(1994) , 10.1128/JB.176.5.1488-1499.1994
Josep Corominas, Josep Clotet, Isabel Fernández-Bañares, Eckhard Boles, Friedrich K. Zimmmermann, Joan J. Guinovart, Joaquín Ariño, Glycogen metabolism in aSaccharomyces cerevisiaephosphoglucose isomerase (pgi1) disruption mutant FEBS Letters. ,vol. 310, pp. 182- 186 ,(1992) , 10.1016/0014-5793(92)81325-G
Frank Baganz, Andrew Hayes, Ronnie Farquhar, Philip R. Butler, David C. J. Gardner, Stephen G. Oliver, Quantitative analysis of yeast gene function using competition experiments in continuous culture. Yeast. ,vol. 14, pp. 1417- 1427 ,(1998) , 10.1002/(SICI)1097-0061(199811)14:15<1417::AID-YEA334>3.0.CO;2-N
MASSOUD RAMEZANI RAD, BETTINA HABBIG, GREGOR JANSEN, UWE HATTENHORST, MATHIAS KROLL, CORNELIS P. HOLLENBERG, Analysis of the DNA sequence of a 34,038 bp region on the left arm of yeast chromosome XV. Yeast. ,vol. 13, pp. 281- 286 ,(1997) , 10.1002/(SICI)1097-0061(19970315)13:3<281::AID-YEA74>3.0.CO;2-E
N Burns, B Grimwade, P B Ross-Macdonald, E Y Choi, K Finberg, G S Roeder, M Snyder, Large-scale analysis of gene expression, protein localization, and gene disruption in Saccharomyces cerevisiae. Genes & Development. ,vol. 8, pp. 1087- 1105 ,(1994) , 10.1101/GAD.8.9.1087