Childhood type 1 diabetes may increase the risk of atopic dermatitis

摘要: SummaryBackground Epidemiological investigations have examined the association between type 1 diabetes mellitus (T1DM) and atopic disease, but obtained conflicting results. Objectives To analyse T1DM dermatitis (AD) in a population-based, retrospective cohort study that investigated hypothesis childhood is risk factor for subsequent AD. Methods From claims data of National Health Insurance programme Taiwan, we identified 3386 patients with newly diagnosed from 1998 to 2011 12 725 randomly selected controls without T1DM. These were frequency matched by age, sex year diagnosis. Both cohorts followed up until end evaluate AD risk. We used Cox proportional hazards regression models AD. Results The overall incidence rate was 1·40-fold (significantly) higher than non-T1DM (3·31 vs. 2·35 per 1000 person years). After adjustment potential factors, remained [adjusted hazard ratio (HR) 1·76, 95% confidence interval (CI) 1·29–2·39] those Compared cohort, more emergency room visits (adjusted HR 30·1, CI 18·7–48·5) or hospitalizations 70·3, 45·6–114·5) had AD. Conclusions This nationwide, demonstrates may increase AD.