Molecular recognition by induced fit: how fit is the concept?

作者: Hans Rudolf Bosshard

DOI: 10.1152/PHYSIOLOGYONLINE.2001.16.4.171

关键词:

摘要: Induced fit explains why biomolecules can bind together even if they are not optimized for binding. However, induced lead to a kinetic bottleneck and does describe every interaction in the absence of prior complementarity. Preselection fitting conformer is an alternative fit.

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